Beyond the Ovaries: Why Exercise Matters for People with PMOS, Previously Known as PCOS

Why Exercise Has An Impact On Your Quality of Life

The recent recategorisation of polycystic ovarian syndrome (PCOS) to polyendocrine metabolic ovarian syndrome (PMOS) solidifies something that those living with the condition and allied health professionals have been saying for years: this condition is far more than a gynaecological disorder.

Those living with PMOS deal with a unique combination of metabolic, dermatological, reproductive and psychological symptoms. As further research is conducted seeking out broader, non-pharmacological treatment options, exercise is consistently put forward as a key pillar in the future of PMOS management.

PMOS

Figure 1. Exercise provides wide-ranging benefits for people living with PMOS, supporting metabolic, cardiovascular, reproductive and psychological health.

Structured exercise is a well-researched and supported treatment for various metabolic conditions, including high blood pressure, diabetes, hyper-lipidemia or high cholesterol, and cardiovascular disease.

In terms of PMOS, exercise offers benefits in both the short and long term; moderate intensity aerobic exercise can acutely improve insulin sensitivity while also contributing to improved blood glucose control in the long term, having a similar effect on blood pressure.

These positive changes in combination with other long terms changes such as improvements in cholesterol, lead to a decreases risk of chronic health conditions and a decrease in systemic inflammation in the body.

Structured supervised exercise offers those living with PMOS a proven, natural treatment option to manage their symptoms and improve their overall quality of life.  Aerobic exercise at a moderate to vigorous intensity, such as walking, jogging or cycling, has been shown in research to decrease insulin resistance, fatigue and other symptoms of PMOS, while also having a positive effect on weight and fertility.

Targeted resistance training improves overall muscle quality and mass, resulting in lasting positive changes in overall metabolic health and activities of daily living. Further, the anti-inflammatory effects of exercise assist in decreasing and managing the systemic low-grade inflammation associated with metabolic conditions, including PMOS.

Fertility complications and hormonal disturbances are common symptoms of PMOS. Thankfully, there is a growing body of evidence showing how exercise can both improve ovulatory function and decrease hyperandrogenism associated with hormonal dysregulation.

Starting a new exercise routine can seem daunting. Exercise Physiologists (EPs) have the education, knowledge and scientific understanding to ensure your efforts are not wasted. EPs ensure your programming aligns with the latest in scientific literature, while also understanding that no two people living with PMOS present with the same symptoms, concerns or goals.

Exercise Physiologists can tailor your program to address other common co-occurring conditions such as endometriosis, chronic fatigue and mental health conditions, treating you as a whole person, and not a single diagnosis.

References

  1. Patten RK, Boyle RA, Moholdt T, Kiel I, Hopkins WG, Harrison CL, Stepto NK. Exercise Interventions in Polycystic Ovary Syndrome: A Systematic Review and Meta-Analysis. Front Physiol. 2020 Jul 7;11:606. doi: 10.3389/fphys.2020.00606. PMID: 32733258; PMCID: PMC7358428.
    • Combined resistance and dietary changes had the greatest effect on free androgen index changes
    • Min 120 min of vigorous int/per week is needed to provide favourable health outcomes for women with PCOS with studies of longer duration required to evaluate outcomes with sustained exercise.
  2. Philbois SV, Ribeiro VB, Tank J, Dos Reis RM, Gerlach DA, Souza HCD. Cardiovascular autonomic modulation differences between moderate-intensity continuous and high-intensity interval aerobic training in women with PCOS: A randomized trial. Front Endocrinol (Lausanne). 2022 Nov 25;13:1024844. doi: 10.3389/fendo.2022.1024844. PMID: 36568110; PMCID: PMC9782449.
    • Both continuous moderate intensity exercise and high intensity interval training can produce positive hormonal and metabolic changes in women with PCOS
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  4. Steenberg DE, Jørgensen NB, Birk JB, Sjøberg KA, Kiens B, Richter EA, Wojtaszewski JFP. Exercise training reduces the insulin-sensitizing effect of a single bout of exercise in human skeletal muscle. J Physiol. 2019 Jan;597(1):89-103. doi: 10.1113/JP276735. Epub 2018 Nov 22. PMID: 30325018; PMCID: PMC6312427.
  5. Moffa S, Sorice GP, Di Giuseppe G, Cinti F, Ciccarelli G, Soldovieri L, Brunetti M, Sonnino R, Nista EC, Gasbarrini A, Pontecorvi A, Mezza T, Giaccari A. A single bout of physical exercise improves 1-hour post-load plasma glucose in healthy young adults. J Endocrinol Invest. 2025 Feb;48(2):455-464. doi: 10.1007/s40618-024-02438-8. Epub 2024 Sep 30. PMID: 39347907; PMCID: PMC11785650.
    • Single bout of aerobic exercise significantly decreased BLG and improved insulin secretion and sensitivity during 1 Hour OGTT